Deadly Fungus Spreads Across US Hospitals, Gains Global Threat Status as Research Warns of Growing Resistance
A highly contagious and lethal fungus known as Candida auris (C. auris) is on a rapid spread across the US, forcing hospitals to shut down their intensive care units due to outbreaks. The fungus, often referred to as a "superbug," has also been identified in at least 60 countries worldwide, with over 7,000 cases reported in the United States alone.
The Centers for Disease Control and Prevention (CDC) has labeled C. auris an "urgent antimicrobial threat" - the first fungal pathogen to receive this designation, highlighting its severe impact on human health. The fungus poses a significant risk to critically ill patients, particularly those on ventilators or with weakened immune systems, with mortality rates estimated to be around 50% once infected.
Researchers warn that outdated diagnostic tools and limited treatments are major contributors to the spread of C. auris, emphasizing the need for novel antifungal agents, improved diagnostics, and immune- and vaccine-based treatment modalities. Dr. Neeraj Chauhan, Dr. Anuradha Chowdhary, and Dr. Michail Lionakis, authors of a recent scientific review, stress that developing effective treatments against this pathogen is essential to improving patient outcomes.
The fungus's ability to survive on human skin, cling to hospital surfaces, and spread easily in healthcare settings makes it difficult to contain. C. auris has already shown resistance to multiple antifungal drugs, further exacerbating the crisis.
Despite the dire situation, researchers have identified potential weaknesses in the fungus that could lead to the development of new treatments. A recent study published by scientists at the University of Exeter found that C. auris activates specific genes to scavenge iron during infection, which could be targeted by future medications.
Health experts caution that strict infection control measures, rapid detection, and continued investment in new treatments remain critical in combating this deadly fungus. While there is still room for cautious optimism, the situation underscores the need for urgent action to address the growing threat of C. auris worldwide.
A highly contagious and lethal fungus known as Candida auris (C. auris) is on a rapid spread across the US, forcing hospitals to shut down their intensive care units due to outbreaks. The fungus, often referred to as a "superbug," has also been identified in at least 60 countries worldwide, with over 7,000 cases reported in the United States alone.
The Centers for Disease Control and Prevention (CDC) has labeled C. auris an "urgent antimicrobial threat" - the first fungal pathogen to receive this designation, highlighting its severe impact on human health. The fungus poses a significant risk to critically ill patients, particularly those on ventilators or with weakened immune systems, with mortality rates estimated to be around 50% once infected.
Researchers warn that outdated diagnostic tools and limited treatments are major contributors to the spread of C. auris, emphasizing the need for novel antifungal agents, improved diagnostics, and immune- and vaccine-based treatment modalities. Dr. Neeraj Chauhan, Dr. Anuradha Chowdhary, and Dr. Michail Lionakis, authors of a recent scientific review, stress that developing effective treatments against this pathogen is essential to improving patient outcomes.
The fungus's ability to survive on human skin, cling to hospital surfaces, and spread easily in healthcare settings makes it difficult to contain. C. auris has already shown resistance to multiple antifungal drugs, further exacerbating the crisis.
Despite the dire situation, researchers have identified potential weaknesses in the fungus that could lead to the development of new treatments. A recent study published by scientists at the University of Exeter found that C. auris activates specific genes to scavenge iron during infection, which could be targeted by future medications.
Health experts caution that strict infection control measures, rapid detection, and continued investment in new treatments remain critical in combating this deadly fungus. While there is still room for cautious optimism, the situation underscores the need for urgent action to address the growing threat of C. auris worldwide.