The Injuries Mount: A Season of Uncertainty for the 49ers The San Francisco 49ers face a potentially disastrous season opener against their division rivals, the Los Angeles Rams.
Coach Kyle Shanahan announced on Wednesday that starting defensive tackle Alfred Collins will miss the entire 2026 season due to a torn patellar tendon suffered in practice earlier this week.
Collins' injury is the latest blow to a team struggling with depth issues on its defense line.